Neurologic dysfunction following cardiac operation with low-flow, low-pressure cardiopulmonary bypass
نویسندگان
چکیده
منابع مشابه
Desflurane improves neurologic outcome after low-flow cardiopulmonary bypass in newborn pigs.
BACKGROUND Despite improvements in neonatal heart surgery, neurologic complications continue to occur from low-flow cardiopulmonary bypass (LF-CPB) and deep hypothermic circulatory arrest (DHCA). Desflurane confers neuroprotection against ischemia at normothermia and for DHCA. This study compared neurologic outcome of a desflurane-based with a fentanyl-based anesthetic for LF-CPB. METHODS Thi...
متن کاملCardiopulmonary bypass and neurologic dysfunction – Results from animal models
Neurologic deficits following cardiac surgery persist as common complications with a significant impact to the patient’s quality of life [1,2]. Clinical manifestations of these deficits are variable, ranging from frank stroke as worst case scenario to the more subtle neurocognitive deficits [2,3]. Despite extensive research in the field, the mechanisms leading to neurologic dysfunctions are not...
متن کاملCardiopulmonary bypass induces neurologic and neurocognitive dysfunction in the rat.
BACKGROUND Neurocognitive dysfunction is a common complication of cardiac surgery using cardiopulmonary bypass (CPB). Elucidating injury mechanisms and developing neuroprotective strategies have been hampered by the lack of a suitable long-term recovery model of CPB. The purpose of this study was to investigate neurologic and neurocognitive outcome after CPB in a recovery model of CPB in the ra...
متن کاملMatrix Metalloproteinase-9 Production following Cardiopulmonary Bypass Was Not Associated with Pulmonary Dysfunction after Cardiac Surgery
BACKGROUND Cardiopulmonary bypass (CPB) causes release of matrix metalloproteinase- (MMP-) 9, contributing to pulmonary infiltration and dysfunction. The aims were to investigate MMP-9 production and associated perioperative variables and oxygenation following CPB. METHODS Thirty patients undergoing elective cardiac surgery were included. Arterial blood was sampled at 6 sequential points (bef...
متن کاملRisk factors for low colloid osmotic pressure during infant cardiopulmonary bypass with a colloidal prime.
Extensive variations of colloid osmotic pressure (COP) measured in the priming as well as during infant cardiopulmonary bypass motivated us to audit clinical and laboratory data to identify the risk factors for low COP at the end of bypass. Data of 73 consecutive infant patients with body weight <10 kg, who underwent elective, first time open-heart surgery between March 2005 and December 2006 w...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1980
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)37952-8